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Reading: S&P report highlights Big Pharma’s concentration risk amid JPM deal flurry
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Life Science Newswire Service™ (LS) > Blog > Life Sciences > Drug development > S&P report highlights Big Pharma’s concentration risk amid JPM deal flurry
Drug development

S&P report highlights Big Pharma’s concentration risk amid JPM deal flurry

By Newsroom
Last updated: January 11, 2026
1 Min Read
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Merck is an A+ credit, a global oncology powerhouse, and still, about half its 2024 pharma revenue came from a single product: Keytruda, a product whose loss of exclusivity will hit around 2028 in the U.S. S&P Global Ratings calls that kind of concentration a “material weakness.”

Merck isn’t alone. A new S&P analysis of 17 top pharmaceutical companies, released today, finds Novo Nordisk in a similar position. More than half of its revenue rides on one product (semaglutide), well above…



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TAGGED:blockbuster drugsbranded pharmabusiness strengthcredit ratingsdrug pricing reformEli LillyGLP-1JPMorgan Healthcare ConferenceKeytrudaleverageM&AMerckNovo Nordiskobesity drugspatent cliffpatent expirationsPharmaceutical acquisitionsproduct concentrationR&D investmentregulatory riskrevenue concentration riskS&P Global RatingstariffsU.S. pricing risk
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