The salting-out method of DNA Extraction is a simple and widely used technique for extracting genomic DNA from various cell types, including blood cells and tissue samples.
Instead of relying on harsh chemicals, this method uses a high concentration of salt to precipitate proteins. Alcohol (usually ethanol or isopropanol) is then added to collect the DNA. The method was first clearly described for human nucleated cells in 1988 by Miller, Dykes, and Polesky, and since then, it has become a standard approach in many labs.
This method was originally developed as a safer alternative to…
