The risk isn’t the method. It’s the variability of the in-house QC organisms.
Imagine this, you’ve set up your weekly Growth Promotion plates and the recovery is not meeting specification. You initiate an investigation to find the root cause: you review pipette calibration and incubator records, contact the media manufacturer, and check your QC culture maintenance documentation. There is little evidence that points to the root cause of the failure and the investigation drags on. The most likely cause is the variability introduced upstream, especially when organisms are…
