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Life Science Newswire Service™ (LS) > Blog > Life Science Magazines > Enhancing Gene Therapy Manufacturing Through Advanced Viral…
Life Science Magazines

Enhancing Gene Therapy Manufacturing Through Advanced Viral…

By Newsroom
Last updated: February 5, 2026
1 Min Read
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Download this free whitepaper to learn more

As gene therapy programs scale, downstream processing remains a critical bottleneck. Manual density gradient ultracentrifugation is time-consuming, variable and difficult to scale — limiting throughput and increasing risk in regulated environments.

This white paper explores how a semi-automated purification workflow using the OptiMATE™ Gradient Maker and Optima™ X-Series Ultracentrifuges helps manufacturers reduce variability, shorten run times and achieve consistent, high-resolution separation of full and empty AAV capsids.

What You’ll Learn

  • Why downstream processing is the biggest challenge in AAV manufacturing
  • How pre-formed gradients can cut ultracentrifuge run times by more than 75%
  • Real-world performance data and case study results
  • How standardized workflows support scalability and GMP compliance

Download the white paper to learn how advanced purification technologies are redefining efficiency and precision in gene therapy manufacturing.


Offered Free by: Beckman Coulter Life Sciences


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