Image: Wikimedia Commons (Public Domain)
In drug discovery, the difference between a breakthrough and a breakdown can be as small as the twist of a bond. Stereochemistry, the three-dimensional arrangement of atoms, governs how otherwise identical molecules behave in the body: whether they bind the intended target, trigger off-targets, or get cleared in minutes rather than hours.
Adam Sanford, Ph.D.
“Shape really does matter,” said Adam Sanford, Ph.D., senior product lead at scientific…