Minimize shear stress and maximize cell viability with Masterflex® peristaltic pumps–precision-engineered for gentle, controlled fluid handling in sensitive cell culture and bioprocessing workflows. Designed to reduce mechanical stress through optimized motor speed, adjustable occlusion, and advanced roller geometry, Masterflex® pumps help researchers maintain experimental integrity, improve reproducibility, and protect valuable cell lines and protein production outcomes.
Shear stress can significantly impact cell viability, morphology, and function—posing challenges for researchers and biomanufacturers alike. This article explores how Masterflex® peristaltic pumps offer a gentle, low-shear solution for fluid handling in sensitive cell culture applications. It examines the effects of pump speed, tubing occlusion, and roller geometry on shear forces, supported by hemolysis testing data. Key findings highlight how optimizing pump configurations—such as using convex rollers, adjustable occlusion settings, and lower motor speeds—can dramatically improve cell viability. Advanced designs like the Masterflex® Cytoflow® pump head further enhance performance by delivering high flow rates with minimal shear, giving researchers greater control over culture conditions and confidence in the reliability of their results.
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